Short Name:
DLS
Instrument Type:
Scattering
Solution Biophysics
Structural Science
Location:
KCL 3
Date of Acquisition:
October 2013
Description:
Dynamic light scattering measures the diffusion rate of molecules or particles in solution by observing the fluctuations in scattered light from a laser passing through a sample. The sensitivity of DLS increases with increasing molecular size, with a typical lower size limit of 0.5 nanometers and upper size limit of 10 micrometers.
Typical applications for DLS include:
- Screening macromolecules prior to crystallization trials
- Measuring the stability of protein samples for NMR analysis
- Monitoring molecular aggregation
- Characterizing nanoparticles
The DynaPro PlateReader II is set up to make these measurements in 96, 384, or 1536 well plates using as little as 5 microliters of sample.
Instrument Image:
